At Vipergen, we utilize innovative, proprietary technologies to transform drug discovery. By enabling screening directly in living cells under physiologically relevant conditions, we expand the target space, improve efficiency, and accelerate lead generation. Our patented platforms set a new standard for tackling even the most complex drug targets.
World-leading provider of small molecule drug discovery services based on DNA-encoded library technologies
Vipergen is finding tractable hits/leads for your pharmaceutical relevant targets, using three proprietary 2nd and 3rd generation DEL technologies. Vipergen is offering different business models, including simple Fee-For-Service.
Do you have an inquiry?
From straightforward Fee-For-Service to comprehensive joint ventures, we provide flexible partnership structures to align with your project’s distinct needs.
-
Innovative screening technologies with Cellular Binder Trap Enrichment (cBTE) & Binder Trap Enrichment (BTE) -
Vipergen’s approach enables the discovery of novel molecules directly in living cells, improving hit rates and drug development efficiency.
-
Vipergen owns exclusive rights to its technology platforms, including YoctoReactor®, BTE, and cBTE, all secured by strong patent positions
Accelerate your drug discovery with DNA-Encoded Libraries
At Vipergen, we specialize in DNA-encoded libraries (DELs) to accelerate small molecule drug discovery. Our cutting-edge DNA-Encoded Chemical Libraries enables the rapid identification of high-affinity compounds through advanced DEL screening technologies. These screening techniques includes our proprietary Cellular Binder Trap Enrichment (cBTE), which allows for the screening inside living cells without the need for a purified target protein.
Maximize the chemical space in drug discovery
Our DNA-encoded libraries are carefully designed to maximize the chemical space in drug discovery. We do this by introducing designer building blocks, which allows for superior chemical diversity in the final library. Our designer building blocks allows the introduction of a broad range of pharmacophores with high variety both in structure and in 3D orientation. Furthermore, our libraries keep physicochemical properties such as molecular weight, solubility, and polar surface area (PSA) in place which gives direct access to lead-like molecules. Our DELs are constructed using the YoctoReactor® which ensures high fidelity, meaning that there is a complete match between compound and DNA code.
Push boundaries of DNA-encoded libraries and drive innovation in drug discovery
By leveraging cBTE as our DEL-screening technology, we provide a powerful and cost-efficient starting point for a drug discovery campaign. At Vipergen, we are pushing the boundaries of DNA-encoded libraries to drive innovation in drug discovery. By combining cutting-edge chemistry and molecular biology, we provide tailored solutions for your research needs. We are committed to drive innovation forward and our screening platform allows us to directly select for inhibitors along with molecular glues and protein-protein inhibitors.
Unlock the full potential of your drug discovery campaign
Partner with us to unlock the full potential of your drug discovery campaign with our DNA-encoded libraries and complimentary screening technologies. Contact us today to learn how our expertise in DNA-encoded library screening can help you discover the next breakthrough.
Cellular Binder Trap Enrichment (cBTE)
-
3rd generation screening technology
-
Screening inside a living cell (unique capability)
-
Physiologically relevant conditions
-
Lower attrition rate
-
No need for purified target protein (unique capability)
-
Broader protein target space
-
Multiplexing (unique capability)
Binder Trap Enrichment (BTE)
-
2nd generation screening technology
-
Solution based (homogenous assay)
-
No matrix binders
-
No target denaturation by immobilization
-
Low false positive rate
-
Multiplexing (unique capability)
YoctoReactor (yR)
-
2nd generation library synthesis technology
-
Chemical diversity by building blocks
-
Physicochemical properties kept in check
-
100% match between code and compound
-
Purification after each synthesis step (unique capability)
-
Low false positive rate
